1. Batman, Combined Gross $1.45 billion, DC Comics
2. Spider-Man, Combined Gross $1.11 billion, Marvel
3. X-Men, Combined Gross 786.5 million, Marvel
4. Superman, Combined Gross $518.1 millions, DC Comics
5. Iron Man, Total Gross, $318.4 million, Marvel
6. Fantastic Four, Combined Gross $286.6 million, Marvel
7. The Incredible Hulk, Combined Gross $266.9 million, Marvel
8. The Incredibles, Total Gross $261.4 million, Disney/Pixar
9. Teenage Mutant Ninja Turtles, Combined Gross $256.2 million, Mirage Studios
10. Hancock, Total Gross: $227.9 million, Sony/Columbia Pictures

Source: CNBC.com